Curated repository for small angle scattering data and models


SASBDB currently contains:


4417

experimental data sets

5734

models
618 experimental data sets on hold
740 models on hold

Small angle scattering (SAS) of X-ray and neutrons provides structural information on biological macromolecules in solution at a resolution of 1-2 nm.
SASBDB is a fully searchable curated repository of freely accessible and downloadable experimental data, which are deposited together with the relevant experimental conditions, sample details, derived models and their fits to the data.

Recent depositions:

SASDVQ6 – Retriever complex

VPS35 endosomal protein-sorting factor-likeVacuolar protein sorting-associated protein 29Vacuolar protein sorting-associated protein 26C experimental SAS data
ALPHAFOLD model
Sample: VPS35 endosomal protein-sorting factor-like monomer, 110 kDa Homo sapiens protein
Vacuolar protein sorting-associated protein 29 monomer, 21 kDa Homo sapiens protein
Vacuolar protein sorting-associated protein 26C monomer, 33 kDa Homo sapiens protein
Buffer: 50 mM Tris, 200 mM NaCl, 1 mM TCEP, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2022 Apr 28
Selective cargo and membrane recognition by SNX17 regulates its interaction with Retriever EMBO Reports (2024)
Martín-González A, Méndez-Guzmán I, Zabala-Zearreta M, Quintanilla A, García-López A, Martínez-Lombardía E, Albesa-Jové D, Acosta J, Lucas M
RgGuinier 5.2 nm
Dmax 21.5 nm
VolumePorod 256 nm3

Third double-stranded RNA-binding domain of Human Double-stranded RNA-specific adenosine deaminase (ADAR1) (residues 716-797, i.e. dsRBD3-short)
Third double-stranded RNA-binding domain of human ADAR1 (residues 716-797, i.e. dsRBD3-short) experimental SAS data
Dimerization of ADAR1 modulates site-specificity of RNA editing Nature Communications 2024 Nov 21 15(1)
Nature Communications 15(1) (2024 Nov 21)
Staphylococcus aureus Fatty Acid Kinase A
Uncharacterized protein SAUSA300_1119 experimental SAS data
Molecular insights into the structure and function of the Staphylococcus aureus fatty acid kinase. J Biol Chem 2024 Oct 24;300(12):107920
J Biol Chem 300(12):107920 (2024 Oct 24)
SEC-SAXS of the fusion protein MPB-MabR(Rv2242) - dimeric peak
Maltose/maltodextrin-binding periplasmic protein (D108A, K109A, E198A, N199A, K265A)Uncharacterized protein Rv2242 experimental SAS data
Domain architecture of the Mycobacterium tuberculosis MabR (Rv2242), a member of the PucR transcription factor family Heliyon 2024 Nov :e40494
Heliyon :e40494 (2024 Nov)
Full-length SARS-CoV-2 5'ge element stem-loop 5 (5_SL5)
full stem-loop 5 of SARS-CoV-2 5'genomic end experimental SAS data
Dissecting the Conformational Heterogeneity of Stem-Loop Substructures of the Fifth Element in the 5'-Untranslated Region of SARS-CoV-2. J Am Chem Soc 2024 Nov 6;146(44):30139-30154
J Am Chem Soc 146(44):30139-30154 (2024 Nov 6)
S9 carboxypeptidase from Bacillus subtilis (4 mg/ml)
Putative acylaminoacyl-peptidase experimental SAS data
Structural adaptations for carboxypeptidase activity in putative S9 acylaminoacyl peptidase from Bacillus subtilis. Int J Biol Macromol 2024 Oct 19;:136734
Int J Biol Macromol :136734 (2024 Oct 19)

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To cite SASBDB refer to: Kikhney AG, Borges CR, Molodenskiy DS, Jeffries CM, Svergun DI (2020) SASBDB: Towards an automatically curated and validated repository for biological scattering data. Protein Science 29(1); 66-75.