| MWexperimental | 221 | kDa |
| MWexpected | 222 | kDa |
| VPorod | 326 | nm3 |
|
log I(s)
3.11×101
3.11×100
3.11×10-1
3.11×10-2
|
s, nm-1
|
Structural Analysis of Pathogenic Mutations Targeting Glu427 of ALDH7A1, the Hot Spot Residue of Pyridoxine-Dependent Epilepsy.
Laciak AR, Korasick DA, Gates KS, Tanner JJ, J Inherit Metab Dis (2019) Europe PMCSASDGJ4 – Human alpha-aminoadipic semialdehyde dehydrogenase (ALDH)7A1 at 2.3 mg/mL
Alpha-aminoadipic semialdehyde dehydrogenase|
|
|
Fits and models
|
|
|
Synchrotron SAXS
data from solutions of
Human alpha-aminoadipic semialdehyde dehydrogenase (ALDH)7A1 at 2.3 mg/mL
in
50 mM HEPES, 100 mM NaCl, 1 mM DTT, 10 mM NAD, 2% (v/v) glycerol, pH 8
were collected
on the
12.3.1 (SIBYLS) beam line
at the Advanced Light Source (ALS) storage ring
(Berkeley, CA, USA)
using a Pilatus3 X 2M detector
at a sample-detector distance of 2 m and
at a wavelength of λ = 0.127 nm
(I(s) vs s, where s = 4πsinθ/λ, and 2θ is the scattering angle).
One solute concentration of 2.30 mg/ml was measured
at 10°C.
The data were normalized to the intensity of the transmitted beam and radially averaged; the scattering of the solvent-blank was subtracted.
X-ray Exposure time = UNKNOWN. Number of frames = UNKNOWN |
|
|||||||||||||||||||||||||||||||||