Curated repository for small angle scattering data and models


SASBDB currently contains:


4657

experimental data sets

5865

models
599 experimental data sets on hold
784 models on hold

Small angle scattering (SAS) of X-ray and neutrons provides structural information on biological macromolecules in solution at a resolution of 1-2 nm.
SASBDB is a fully searchable curated repository of freely accessible and downloadable experimental data, which are deposited together with the relevant experimental conditions, sample details, derived models and their fits to the data.

Recent depositions:

SASDVU5 – Marchantia polymorpha Auxin Response Factor 3 in complex with high affinity DNA

Auxin response factorHigh Affinity ARF binding sequence inverted repeat with 6 nucleotide spacing experimental SAS data
SWISSMODEL model
Sample: Auxin response factor monomer, 46 kDa Marchantia polymorpha protein
High Affinity ARF binding sequence inverted repeat with 6 nucleotide spacing dimer, 12 kDa DNA
Buffer: 20 mM Tris-HCl, 150 mM NaCl, 1 mM DTT, pH: 8
Experiment: SAXS data collected at BL11 - NCD, ALBA on 2019 Dec 3
The structure and function of the DNA binding domain of class B MpARF2 share more traits with class A AtARF5 than to that of class B AtARF1. Structure (2025)
Crespo I, Malfois M, Rienstra J, Tarrés-Solé A, van den Berg W, Weijers D, Boer DR
RgGuinier 3.1 nm
Dmax 8.4 nm
VolumePorod 67 nm3

Human DNA methyltransferase 3 beta DNMT3B (413-853) and DNA methyltransferase 3-like DNMT3L (178-379) in complex with histone H3
Histone H3.3DNA methyltransferase 3-like (178-379)DNA methyltransferase 3 beta (413-853) experimental SAS data
Histone modification-driven structural remodeling unleashes DNMT3B in DNA methylation. Sci Adv 2025 Mar 28;11(13):eadu8116
Sci Adv 11(13):eadu8116 (2025 Mar 28)
RNA Device 43 in ligand-bound state (holo-D43)
RNA Device 43 in ligand-bound state experimental SAS data
Structural investigation of an RNA device that regulates PD-1 expression in mammalian cells. Nucleic Acids Res 2025 Feb 27;53(5)
Nucleic Acids Res 53(5) (2025 Feb 27)
Trypanosoma brucei ESAG4 membrane-proximal Venus Fly Trap domain 2 (VFT2)
adenylate cyclase experimental SAS data
Biophysical analysis of the membrane-proximal Venus Flytrap domain of ESAG4 receptor-like adenylate cyclase from Trypanosoma brucei. Mol Biochem Parasitol 2024 Dec;260:111653
Mol Biochem Parasitol 260:111653 (2024 Dec)
Immunoglobulin light chain AL55
Immunoglobulin light chain AL55 experimental SAS data
A conformational fingerprint for amyloidogenic light chains eLife 2025 Mar 03 13
eLife 13 (2025 Mar 03)
Alpha-1-acid glycoprotein at 283 K
Alpha-1-acid glycoprotein 1 experimental SAS data
SAXS data based glycosylated models of human alpha-1-acid glycorprotein, a key player in health, disease and drug circulation. J Biomol Struct Dyn 2025 Mar 8;:1-15
J Biomol Struct Dyn :1-15 (2025 Mar 8)

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To cite SASBDB refer to: Kikhney AG, Borges CR, Molodenskiy DS, Jeffries CM, Svergun DI (2020) SASBDB: Towards an automatically curated and validated repository for biological scattering data. Protein Science 29(1); 66-75.