Curated repository for small angle scattering data and models


SASBDB currently contains:


4903

experimental data sets

6098

models
552 experimental data sets on hold
768 models on hold

Small angle scattering (SAS) of X-ray and neutrons provides structural information on biological macromolecules in solution at a resolution of 1-2 nm.
SASBDB is a fully searchable curated repository of freely accessible and downloadable experimental data, which are deposited together with the relevant experimental conditions, sample details, derived models and their fits to the data.

Recent depositions:

SASDXH4 – Mouse complex murine Immunoglobulin E (IgE) antibody with profilin (without HisTAG)

Murine Immunoglobulin E (IgE) antibodiesProfilin-2 experimental SAS data
SREFLEX model
Sample: Murine Immunoglobulin E (IgE) antibodies monomer, 165 kDa Mus musculus protein
Profilin-2 monomer, 18 kDa Hevea brasiliensis protein
Buffer: 20 mM Tris, 50 mM NaCl, pH: 8.4
Experiment: SAXS data collected at EMBL P12, PETRA III on 2025 Apr 11
Allergen-induced structural rearrangements in IgE: insights from SAXS and molecular dynamics. Int J Biol Macromol :147658 (2025)
Gómez-Velasco H, García-Ramírez B, Siliqi D, Graewert MA, Quintero-Martinez A, Ortega E, Rodríguez-Romero A
RgGuinier 5.7 nm
Dmax 19.9 nm
VolumePorod 450 nm3

Apolipoprotein A-I monomer, C-terminally truncated
Apolipoprotein A-I experimental SAS data
The structure of the apolipoprotein A-I monomer provides insights into its oligomerisation and lipid-binding mechanisms Journal of Molecular Biology 2025 Aug :169394
Journal of Molecular Biology :169394 (2025 Aug)
Dengue Virus 2 (DENV2) complex 5'-3'
DENV2 complex 5'-3' experimental SAS data
Structural Dynamics of Dengue Virus UTRs and Their Cyclization. Biophys J 2025 Sep 5;
Biophys J (2025 Sep 5)
UvrB (UvrABC system protein B)
UvrABC system protein B experimental SAS data
Inhibition of Mycobacterium tuberculosis UvrB by small molecules: Potent NER disruption and structural insights into dimer conformation. Int J Biol Macromol 2025 Sep 3;:147338
Int J Biol Macromol :147338 (2025 Sep 3)
Peroxisomal targeting signal receptor Pex5 from P. pastoris
Peroxisomal targeting signal receptor experimental SAS data
Structure of Pex8 in complex with peroxisomal receptor Pex5 reveals its essential role in peroxisomal cargo translocation 2025 Sep 02
(2025 Sep 02)
Transthyretin tetramer with over-saturated tolcapone
TransthyretinTolcapone experimental SAS data
Differentiating the solution structures and stability of transthyretin tetramer complexed with tolcapone and tafamidis using SEC-SWAXS and NMR. J Appl Crystallogr 2025 Aug 1;58(Pt 4):1373-1383
J Appl Crystallogr 58(Pt 4):1373-1383 (2025 Aug 1)

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To cite SASBDB refer to: Kikhney AG, Borges CR, Molodenskiy DS, Jeffries CM, Svergun DI (2020) SASBDB: Towards an automatically curated and validated repository for biological scattering data. Protein Science 29(1); 66-75.