Curated repository for small angle scattering data and models


SASBDB currently contains:


4706

experimental data sets

5899

models
602 experimental data sets on hold
840 models on hold

Small angle scattering (SAS) of X-ray and neutrons provides structural information on biological macromolecules in solution at a resolution of 1-2 nm.
SASBDB is a fully searchable curated repository of freely accessible and downloadable experimental data, which are deposited together with the relevant experimental conditions, sample details, derived models and their fits to the data.

Recent depositions:

SASDX72 – Fatty acyl-CoA synthetase FadD5 with 2 mM coenzyme A (CoA)

Probable fatty-acid-CoA ligase FadD5 (Fatty-acid-CoA synthetase) (Fatty-acid-CoA synthase) experimental SAS data
ALPHAFOLD model
Sample: Probable fatty-acid-CoA ligase FadD5 (Fatty-acid-CoA synthetase) (Fatty-acid-CoA synthase) dimer, 123 kDa Mycobacterium tuberculosis (strain … protein
Buffer: 20 mM HEPES, 500 mM NaCl, 5 mM MgCl2, 1 mM β-mercaptoethanol, 2 mM coenzyme A (CoA), pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2022 Oct 20
Structural enzymological studies of the long chain fatty acyl-CoA synthetase FadD5 from the mce1 operon of Mycobacterium tuberculosis. Biochem Biophys Res Commun 769:151960 (2025)
Rahman MA, Dalwani S, Venkatesan R
RgGuinier 3.7 nm
Dmax 12.0 nm
VolumePorod 210 nm3

Ustilago maydis Jps1 protein
Uncharacterized protein experimental SAS data
Specific phosphoinositide interaction of Jps1 is a key feature during unconventional secretion in Ustilago maydis Journal of Biological Chemistry 2025 May :110215
Journal of Biological Chemistry :110215 (2025 May)
Ser48-phosphorylated N-terminal domain of transactive response DNA-binding protein 43 (TDP-43)
TAR DNA-binding protein 43 experimental SAS data
Semi-synthesis of TDP-43 reveals the effects of phosphorylation in N-terminal domain on self-association Communications Chemistry 2025 Apr 25 8(1)
Communications Chemistry 8(1) (2025 Apr 25)
Aromatic-L-amino-acid decarboxylase R347Q bound to pyridoxal 5'-phosphate (PLP)
Aromatic-L-amino-acid decarboxylase (R347Q) experimental SAS data
The CRISPR-Cas9 knockout DDC SH-SY5Y in vitro model for AADC deficiency provides insight into the pathogenicity of R347Q and L353P variants: a cross-sectional structural and functional analysis. FEBS J 2025 May 3;
FEBS J (2025 May 3)
BRUTUS-LIKE2 N-Terminal Region (BTSL2-N)
Zinc finger protein BRUTUS-like At1g18910 experimental SAS data
Iron-sensing and redox properties of the hemerythrin-like domains of Arabidopsis BRUTUS and BRUTUS-LIKE2 proteins. Nat Commun 2025 Apr 24;16(1):3865
Nat Commun 16(1):3865 (2025 Apr 24)
The Ig-like C2-type 3 and Ig-like C2-type 4 domains (Ig34WT) of Palladin
Palladin experimental SAS data
Integrated structural model of the palladin-actin complex using XL-MS, docking, NMR, and SAXS. Protein Sci 2025 May;34(5):e70122
Protein Sci 34(5):e70122 (2025 May)

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To cite SASBDB refer to: Kikhney AG, Borges CR, Molodenskiy DS, Jeffries CM, Svergun DI (2020) SASBDB: Towards an automatically curated and validated repository for biological scattering data. Protein Science 29(1); 66-75.