| MWI(0) | 17 | kDa |
| MWexpected | 19 | kDa |
| VPorod | 41 | nm3 |
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log I(s)
4.61×102
4.61×101
4.61×100
4.61×10-1
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s, nm-1
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Biophysical insights from a single chain camelid antibody directed against the Disrupted-in-Schizophrenia 1 protein.
Yerabham ASK, Müller-Schiffmann A, Ziehm T, Stadler A, Köber S, Indurkhya X, Marreiros R, Trossbach SV, Bradshaw NJ, Prikulis I, Willbold D, Weiergräber OH, Korth C, PLoS One 13(1):e0191162 (2018) Europe PMCSASDDK7 – Disrupted-in-Schizophrenia 1 protein (DISC1 12d2)
Disrupted- in-schizophrenia 1 (DISC1 12D2) 691-836|
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Fits and models
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Synchrotron SAXS data from solutions of the disrupted-in-Schizophrenia 1 protein (DISC1 12d2) in 25 mM Tris-HCl, 150 mM NaCl, 1mM DTT, pH 7.4 were collected on the EMBL P12 beam line at the PETRA III storage ring (Hamburg, Germany) using a Pilatus 1M-W detector at a sample-detector distance of 3 m and at a wavelength of λ = 0.123987 nm (l(s) vs s, where s = 4πsinθ/λ, and 2θ is the scattering angle). One solute concentration of 2.80 mg/ml was measured at 20°C. 20 successive 0.095 second frames were collected. The data were normalized to the intensity of the transmitted beam and radially averaged; the scattering of the solvent-blank was subtracted.
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