SASDPG4 – Alpha-1-acid glycoprotein at 283 K

Alpha-1-acid glycoprotein 1

MW^experimental	39	kDa
MW^expected	22	kDa
V^Porod	83	nm³

log I(s) 1.73×10⁵ 1.73×10⁴ 1.73×10³ 1.73×10²

Alpha-1-acid glycoprotein 1 small angle scattering data

s, nm^-1

Log plot Log-Log plot

ln I(s)

Alpha-1-acid glycoprotein 1 Guinier plot

ln 1.74×10⁵ R_g: 2.6 nm 0 (2.6 nm)^-2 s²

(sR_g)²I(s)/I(0)

1.104 0 √3 sR_g

p(r)	R_g: 2.5 nm 0 D_max: 7.5 nm

Data validation

Fits and models

log I(s)

s, nm^-1

log I(s)	s, nm^-1
+3 Δ/σ -3	s, nm^-1

Alpha-1-acid glycoprotein 1 OTHER [STATIC IMAGE] model

SAXS data from solutions of Alpha-1-acid glycoprotein in phosphate buffered saline, pH 7.4 were were collected using an Anton Paar SAXSpace at the CSIR Institute of Microbial Technology (IMTech; Chandigarh, India) equipped with a Mythen 1K detector at a sample-detector distance of 0.3 m and at a wavelength of λ = 0.154 nm (I(s) vs s, where s = 4πsinθ/λ, and 2θ is the scattering angle). One solute concentration of 3.50 mg/ml was measured at 10°C. One 3600 second frame was collected. The data were normalized to the intensity of the transmitted beam and radially averaged; the scattering of the solvent-blank was subtracted.

Note: This is a heavily glycosylated protein, so generalized results could be anamolous.

Alpha-1-acid glycoprotein 1 (AGP)
Mol. type		Protein
Organism		Homo sapiens
Olig. state		Monomer
Mon. MW		21.6 kDa

UniProt		P02763 (19-183)
Sequence		FASTA