Extended q‐range X‐ray Scattering Reveals High‐Resolution Structural Details of Biomacromolecules in Aqueous Solutions

Chen J, Borkiewicz O, Grishaev A, Zhang F, Bera M, Ruett U, Levin I, Chemistry – A European Journal (2023) DOI

SASDRA2 – Alpha cyclodextrin - 12.5 mg/ml aqueous solution measured to 235 inverse nm

alpha cyclodextrin
MWexperimental 1 kDa
MWexpected 1 kDa
log I(s) 1.68×10-4 1.68×10-5 1.68×10-6 1.68×10-7
alpha cyclodextrin small angle scattering data  s, nm-1
ln I(s)
alpha cyclodextrin Guinier plot ln 1.68×10-4 Rg: 0.6 nm 0 (0.6 nm)-2 s2
(sRg)2I(s)/I(0)
alpha cyclodextrin Kratky plot 1.104 0 3 sRg

Data validation


There are no models related to this curve.

Synchrotron WAXS data from solutions of alpha-cyclodextrin in water, pH 7 were collected on the 11-ID-B beam line at the Advanced Photon Source (APS), Argonne National Laboratory (Lemont, IL, USA) using a Perkin–Elmer amorphous Si detector at a sample-detector distance of 0.188 m and at a wavelength of λ = 0.0211 nm (I(s) vs s, where s = 4πsinθ/λ, and 2θ is the scattering angle). One solute concentration of 12.50 mg/ml was measured at 20°C. 10 successive 180 second frames were collected. The data were normalized to the intensity of the transmitted beam and radially averaged; the scattering of the solvent-blank was subtracted.

The data displayed in this entry were generated from merging SAXS data with extended-range WAXS data. The WAXS collection parameters are described above. The corresponding SAXS data were collected on the 15-ID-D beam line at the Advanced Photon Source (APS), Argonne National Laboratory (Lemont, IL, USA) using a Pilatus 300K detector at a sample-detector distance of 0.57 m and at a wavelength of λ = 0.06199 nm at 20°C. 200 successive 1 second frames were collected. Note: The source/downloadable merged SAXS/WAXS data provided in this entry have s-units of inverse Å. https://pubchem.ncbi.nlm.nih.gov/compound/alpha-Cyclodextrin

Tags: softmatter
alpha cyclodextrin (ACD)
Mol. type   Other
Olig. state   Monomer
Mon. MW   1.0 kDa
Chemical formula