SAXS data from solutions of calcium/calmodulin-dependent protein kinase type II alpha (CaMKIIα) WT hub domain with HOCPCA in 20 mM MES, 150 mM NaCl, 1 mM DTT, 1 mM HOCPCA, pH 6 were collected using a Xenocs BioXolver L with MetalJet (University of Copenhagen, Department of Drug Design and Pharmacology) equipped with a Pilatus3 R 300K detector at a sample-detector distance of 1.0 m and at a wavelength of λ = 0.13428 nm (I(s) vs s, where s = 4πsinθ/λ, and 2θ is the scattering angle). One solute concentration of 2.90 mg/ml was measured at 25°C. 10 successive 60 second frames were collected. The data were normalized to the intensity of the transmitted beam and radially averaged; the scattering of the solvent-blank was subtracted.
The data is a merge from data collected at three different configurations. In addition to the listed, data was collected on the same sample with sample-detector distance 0.610 m (10 frames of 60 s exposure) and with sample-detector distance of 1.4355 m (10 frames of 120 sec exposure). The resulting data is a merge of the data from the three configurations.
These data were collected for comparison with the CaMKIIa WT hub without ligand.
HOCPCA: https://pubchem.ncbi.nlm.nih.gov/compound/3-Hydroxycyclopent-1-ene-1-carboxylic-acid
s, nm-1
