Zip file contains the SAXS multiple data set of native liposomes composed of lipids extracted from A/Puerto Rico/8/34 (H1N1) virus envelope loaded with M1 protein. Experimental small-angle scattering data are the files with extensions (*.dat). The best fits of the SAXS curves obtained by BILMIX program are the files with extenstions (*.fit). The restored electron density profiles of the lipid bilayer before and after loading with M1. The molar lipid/M1 ratios are the following: (1) no M1, (2) 20:1, (3) 4:1 (4) 2.6:1.