Splicing factor, proline- and glutamine-rich

SFPQ-QM-TM protein

Organism: Homo sapiens

Monomeric molecular weight: 37.8 kDa

Oligomeric state: Monomer

Total molecular weight: 37.8 kDa

UniProt: P23246 (276-598)

Sequence:

EGFKANLSLLRRPGEKTYTQRCRLF VGNLPADITEDEFKRLFAKYGEPGEVFINKGKGFGFIKLESRALAEIAKA ELDDTPMRGRQLRVRFATHAAALSVRNLSPYVSNELLEEAFSQFGPIERA VVIVDDRGRSTGKGIVEFASKPAARKAFERCSEGVFLLTTTPRPVIVEPL EQLDDEDGLPEKLAQKNPMYQKERETPPRFAQAGTFEYEYSQRWKSLDEM EKQQREQVEKNMKDAKDKLESEMEDAYAEAQANLARQDAMRRQEEARRAE ELHNQEMQKRKEMQLRQEEERRRREEEMMIRQREMEEQMRRQREESYS

Human SPPQ(276-598) harbouring mutations L535A, L539A, L546A and M549A, plus mutations H483A, H528A and H530A