Transient receptor potential cation channel subfamily V member 4

TRPV4 protein

Organism: Gallus gallus

Monomeric molecular weight: 32.5 kDa

Oligomeric state: Monomer

Total molecular weight: 32.5 kDa

UniProt: A0A1D5PXA5 (98-382)

Sequence:

TYRQHPSENKRWRRRVVEKPVAGTKGPAPNPPPILKVFNRPILFDIVSRGSPDGLEGLLSFLLTHKKRLTDEEFREPSTGKTteCLPKALLNLSAGRNDTIPILLDIAEKTGNMREFINSPFRDVYYRGQTALHIAIERRCKHYVELLVEKGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQPHIVHYLTENGHKQADLRRQDSRGNTVLHALVAIADNTRENTKFVTKMYDLLLIKCAKLFPDTNLEALLNNDGLSPLMMAAKTGKIGIFQHIIRREIAD

The molecule contains residues T98-D382 of G. gallus TRPV4, which includes a PIP2 binding site (K107-R111), a proline-rich region (T121-V134) and an Ankryin repeat domain.