Transient receptor potential cation channel subfamily V member 4

TRPV4 protein

Organism: Gallus gallus

Monomeric molecular weight: 37.3 kDa

Oligomeric state: Monomer

Total molecular weight: 37.3 kDa

UniProt: A0A1D5PXA5 (55-382)

Sequence:

MKFHGAFRKGPPKPMELLESTIYESSVVPAPKKAPMDSLFDYGTYRQHPSENKRWRRRVVEKPVAGTKGPAPNPPPILKVFNRPILFDIVSRGSPDGLEGLLSFLLTHKKRLTDEEFREPSTGKTteCLPKALLNLSAGRNDTIPILLDIAEKTGNMREFINSPFRDVYYRGQTALHIAIERRCKHYVELLVEKGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQPHIVHYLTENGHKQADLRRQDSRGNTVLHALVAIADNTRENTKFVTKMYDLLLIKCAKLFPDTNLEALLNNDGLSPLMMAAKTGKIGIFQHIIRREIAD

The molecule contains residues M55-D382 of G. gallus TRPV4, which includes a PIP2 binding site (K107-R111), a proline-rich region (T121-V134) and an Ankryin repeat domain (F135-D382).