DGQHR domain-containing protein

DpdB protein

Organism: Salmonella enterica subsp. enterica serovar Montevideo

Monomeric molecular weight: 44.2 kDa

Oligomeric state: Dimer

Total molecular weight: 88.5 kDa

UniProt: A0A3Y0E1G8 (1-375)

Sequence:

MSEFRVPALRIRQGEKRQLFSLAIEGKQINKIAAISRIRRGDENLVGYQRPEVRSHIKEIQRYIESSNPMIPNPVIIAFDQRVRFEPLMENSDMGHLVIPYSEDANFEKPGFIVDGQQRTAALREADINSFMMPVSAFIANDAEEQREQFMLVNSTKPLPKTLLYELAPHTHGRLPSDLQLRKFPSLLTQRLNFGEGPLAGRIKTATNPDGVIADNSMIKMIDSSLREGALYRFRDPATGLGDEAKMVKLLNNFWSAVETVFTDDWDKKPRNSRLLHGVGILALGSLMDEIDQVHQDYKGEPGWTEIPSYTRFVEELHRIKPLCAWSSGVWNLGTDIDGQPIVRKWNEVQNLSKDISLVTDYLVTNYIKTANADIEGRAAALEHHHHHH

DpdB is a DNA binding ATPase. The exact function is unknown, but DpdB, ATP hydrolysis and DpdA are all required for preQ0 incorporation into DNA. The protein construct used for SAXS contains a C-terminal polyhistidine tag.