Replicase polyprotein 1ab (Non-structural protein 10)

Nsp10 protein

Organism: Severe acute respiratory syndrome coronavirus (SARS-CoV)

Monomeric molecular weight: 16.1 kDa

Oligomeric state: Monomer

Total molecular weight: 16.1 kDa

UniProt: P0C6X7 (4231-4378)

Sequence:

AGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLNGFAV

The protein construct used for SAXS (as per UniProt convention) contains a C-terminal extension (SADASTFLN) derived from Nsp12 plus an additional four exogenous (GFAV) amino acids at the C-terminus.