T. brucei spp.-specific protein

ISG43 protein

Organism: Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)

Monomeric molecular weight: 38.4 kDa

Oligomeric state: Monomer

Total molecular weight: 38.4 kDa

UniProt: C9ZNA4 (22-349)

Sequence:

MGSSHHHHHHSSGLVPRGSHMHVGKARASETQTNEAEDKLSRAAADVLCIMTDLTRKVVNPLADRLAELAAEDTANITRDAELVNTYVDDIDGMLGKDSDDPDGTKKRIKELCDGAKTKVKDMPENARNREASIKEKAVKAKESGKKTLEGTEASEGGNPVVGLKEVMSSYCRGGRKCEEGVVSSTLDPPEGEISCTNVTLDEKEKWISTLMVEAGANWTTSKPKKVVNCSTAGEPPCTPLDQWGTHYNDTKSHVVRIVGELDESYKDMLICENQLLLVYKIHKGLQEEKNHSEIISEGERISNRTLDVLIGMSGGHRSSSLEDGVNNTDLQDLEEARTLFAKKRRWIM

The protein construct used for SAXS contains an N-terminal polyhistidine tag (MGSSHHHHHHSSGLVPRGSHM)