Structural and functional characterization of the Severe fever with thrombocytopenia syndrome virus L protein

Vogel D, Thorkelsson S, Quemin E, Meier K, Kouba T, Gogrefe N, Busch C, Reindl S, Günther S, Cusack S, Grünewald K, Rosenthal M
(2020 Mar 03)

doi: 10.1101/2020.03.02.973065
Submitted to SASBDB: 2020 Mar 23
Published in SASBDB:

SASDHQ8 – Severe fever with thrombocytopenia syndrome virus (SFTSV) full-length L protein

Severe fever with thrombocytopenia syndrome virus L protein - RNA-dependent RNA polymerase experimental SAS data
Severe fever with thrombocytopenia syndrome virus L protein - RNA-dependent RNA polymerase Kratky plot
Sample: Severe fever with thrombocytopenia syndrome virus L protein - RNA-dependent RNA polymerase monomer, 238 kDa SFTS virus AH12 protein
Buffer: 50 mM HEPES(NaOH) pH 7.0, 500 mM NaCl, 5% (w/v) glycerol, and 2 mM dithiothreitol, pH: 7
Experiment: SAXS data collected at EMBL P12, PETRA III on 2019 Sep 13
RgGuinier 4.5 nm
Dmax 14.3 nm
VolumePorod 483 nm3