Atomic structure of, and valine binding to the regulatory ACT domain of the Mycobacterium tuberculosis Rel protein.

Shin J, Singal B, Manimekalai MSS, Chen MW, Ragunathan P, Grüber G
FEBS J (2020 Oct 17)
PMID: 33067840
doi: 10.1111/febs.15600 		Submitted to SASBDB: 2020 Mar 16
Published in SASBDB:

SASDHJ8 – ACT domain of the Mycobacterium tuberculosis Rel protein

ACT domain of Rel protein (Bifunctional (p)ppGpp synthase/hydrolase RelA) experimental SAS data
ACT domain of Rel protein (Bifunctional (p)ppGpp synthase/hydrolase RelA) Kratky plot
Sample: ACT domain of Rel protein (Bifunctional (p)ppGpp synthase/hydrolase RelA) dimer, 20 kDa Mycobacterium tuberculosis protein
Buffer: 50 mM Tris-HCl, 350 mM NaCl, 5% glycerol, 1 mM DTT, pH: 8.5
Experiment: SAXS data collected at Bruker Nanostar, Nanyang Technological University on 2018 Jun 7
RgGuinier 1.9 nm
Dmax 6.1 nm
VolumePorod 29 nm3