The three-way junction structure of the HIV-1 PBS-segment binds host enzyme important for viral infectivity.

Song Z, Gremminger T, Singh G, Cheng Y, Li J, Qiu L, Ji J, Lange MJ, Zuo X, Chen SJ, Zou X, Boris-Lawrie K, Heng X
Nucleic Acids Res (2021 May 12)
PMID: 33978756
doi: 10.1093/nar/gkab342
Submitted to SASBDB: 2020 Sep 3
Published in SASBDB:

SASDJU7 – HIV-1 Primer Binding Site (PBS)-Segment RNA

Primer Binding Site-Segment experimental SAS data
DAMMIF model
Sample: Primer Binding Site-Segment monomer, 33 kDa HIV-1: pNL4-3 RNA
Buffer: 10 mM Tris, 140 mM KCl, 10 mM NaCl, 1 mM MgCl2, pH: 7.5
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2015 Jul 29
RgGuinier 3.4 nm
Dmax 12.8 nm
VolumePorod 87 nm3