The allosteric modulation of Complement C5 by knob domain peptides.

Macpherson A, Laabei M, Ahdash Z, Graewert MA, Birtley JR, Schulze ME, Crennell S, Robinson SA, Holmes B, Oleinikovas V, Nilsson PH, Snowden J, Ellis V, Mollnes TE, Deane CM, Svergun D, Lawson AD, van den Elsen JM
Elife 10 (2021 Feb 11)
PMID: 33570492
doi: 10.7554/eLife.63586
Submitted to SASBDB: 2020 Jul 31
Published in SASBDB:

SASDJA6 – Complement C5

Complement C5 experimental SAS data
CUSTOM IN-HOUSE model
Sample: Complement C5 monomer, 186 kDa Homo sapiens protein
Buffer: 20mM Tris pH, 75mM NaCl, and 3% glycerol, pH: 7.4
Experiment: SAXS data collected at EMBL P12, PETRA III on 2019 Sep 12
RgGuinier 4.8 nm
Dmax 17.6 nm
VolumePorod 392 nm3