Capturing the Conformational Ensemble of the Mixed Folded Polyglutamine Protein Ataxin-3.

Sicorello A, Różycki B, Konarev PV, Svergun DI, Pastore A
Structure (2020 Oct 13)

PMID: 33065068 doi: 10.1016/j.str.2020.09.010

Submitted to SASBDB: 2020 Aug 17 Published in SASBDB: 2020 Oct 28

SASDJ47 – Polyglutamine protein ataxin-3 (Q13) Sample: Ataxin-3 (polyglutamine protein ataxin-3 (Q13)) monomer, 41 kDa Homo sapiens protein Buffer: 20 mM sodium phosphate buffer, 2 mM TCEP, 5% glycerol, pH: 6.5 Experiment: SAXS data collected at EMBL P12, PETRA III on 2018 May 24 RgGuinier 4.0 nm Dmax 14.1 nm VolumePorod 79 nm3

SASDJ57 – Polyglutamine protein ataxin-3 (Q54) Sample: Ataxin-3 (polyglutamine protein ataxin-3 (Q54)) monomer, 46 kDa protein Buffer: 20 mM sodium phosphate buffer, 2 mM TCEP, 5% glycerol, pH: 6.5 Experiment: SAXS data collected at EMBL P12, PETRA III on 2018 May 24 RgGuinier 4.2 nm Dmax 15.5 nm VolumePorod 89 nm3