Inter-domain Flexibility of Chikungunya Virus nsP2 Helicase-Protease Differentially Influences Viral RNA Replication and Infectivity.

Law YS, Wang S, Tan YB, Shih O, Utt A, Goh WY, Lian BJ, Chen MW, Jeng US, Merits A, Luo D
J Virol (2020 Dec 16)
PMID: 33328310
doi: 10.1128/JVI.01470-20 		Submitted to SASBDB: 2020 Oct 29
Published in SASBDB:

SASDK82 – Full-length nonstructural protein 2 (nsP2) of Chikungunya virus (CHIKV)

NsP2 protein experimental SAS data
CORAL model
Sample: NsP2 protein monomer, 90 kDa Chikungunya virus protein
Buffer: 20 mM Hepes pH 7.4, 150 mM NaCl, 1 mM DTT, 5% glycerol, pH: 7.4
Experiment: SAXS data collected at 23A, Taiwan Photon Source, NSRRC on 2019 Aug 10
RgGuinier 3.9 nm
Dmax 12.0 nm
VolumePorod 134 nm3