The structural plasticity of nucleic acid duplexes revealed by WAXS and MD.

He W, Chen YL, Pollack L, Kirmizialtin S
Sci Adv 7(17) (2021 Apr)
PMID: 33893104
doi: 10.1126/sciadv.abf6106
Submitted to SASBDB: 2020 Oct 29
Published in SASBDB:

SASDKF2 – Mixed-sequence DNA dimer (25 base pair DNA)

Mixed-sequence 25 base-paired DNA experimental SAS data
Mixed-sequence 25 base-paired DNA Kratky plot
Sample: Mixed-sequence 25 base-paired DNA dimer, 16 kDa DNA
Buffer: 1.0 mM MgCl2, 10 mM Na-MOPS and 20uM EDTA, pH: 7
Experiment: SAXS data collected at 16-ID (LiX), National Synchrotron Light Source II (NSLS-II) on 2019 Jun 7
RgGuinier 2.0 nm
Dmax 7.8 nm
VolumePorod 17 nm3

SASDKG2 – AT-sequence DNA dimer (25 base pair DNA)

AT-sequence 25 base-paired DNA experimental SAS data
AT-sequence 25 base-paired DNA Kratky plot
Sample: AT-sequence 25 base-paired DNA dimer, 16 kDa DNA
Buffer: 1.0 mM MgCl2, 10 mM Na-MOPS and 20uM EDTA, pH: 7
Experiment: SAXS data collected at 16-ID (LiX), National Synchrotron Light Source II (NSLS-II) on 2019 Jun 7
RgGuinier 2.1 nm
Dmax 8.0 nm
VolumePorod 16 nm3