Structural, thermodynamic and functional studies of human 71 kDa heat shock cognate protein (HSPA8/hHsc70)

Silva N, de Camargo Rodrigues L, Dores-Silva P, Montanari C, Ramos C, Barbosa L, Borges J
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics :140719 (2021 Sep)

doi: 10.1016/j.bbapap.2021.140719 		Submitted to SASBDB: 2021 Mar 9
Published in SASBDB:

SASDL42 – Human Heat Shock Cognate 71 kDa Protein (HSPA8 / Hsc70)

Heat shock cognate 71 kDa protein experimental SAS data
Human Heat Shock Cognate 71 kDa Protein (HSPA8 / Hsc70) Rg histogram
Sample: Heat shock cognate 71 kDa protein monomer, 71 kDa Homo sapiens protein
Buffer: 25 mM Tris HCl, 50 mM NaCl, 5 mM Sodium Phosphate, 5 mM KCl, pH: 7.5
Experiment: SAXS data collected at SAXS1 Beamline, Brazilian Synchrotron Light Laboratory on 2018 May 18
RgGuinier 3.7 nm
Dmax 11.5 nm
VolumePorod 111 nm3

SASDL52 – Human Heat Shock 70 kDa Protein 1A (Hsp70-1A/HSPA1A)

Heat shock 70 kDa protein 1A experimental SAS data
DAMMIN model
Sample: Heat shock 70 kDa protein 1A monomer, 70 kDa Homo sapiens protein
Buffer: 25 mM Tris HCl, 50 mM NaCl, 5 mM Sodium Phosphate, 5 mM KCl, pH: 7.5
Experiment: SAXS data collected at SAXS1 Beamline, Brazilian Synchrotron Light Laboratory on 2018 May 18
RgGuinier 3.7 nm
Dmax 11.0 nm
VolumePorod 138 nm3