Why are the 2-oxoacid dehydrogenase complexes so large? Generation of an active trimeric complex

Marrott N, Marshall J, Svergun D, Crennell S, Hough D, van den Elsen J, Danson M
Biochemical Journal 463(3):405-412 (2014 Oct 10)

doi: 10.1042/BJ20140359
Submitted to SASBDB: 2021 Apr 12
Published in SASBDB:

SASDLH3 – Truncated Thermoplasma E2 catalytic core

Regulatory protein E2 experimental SAS data
CUSTOM IN-HOUSE model
Sample: Regulatory protein E2 trimer, 73 kDa Human papillomavirus type … protein
Buffer: 50 mM Tris ⁄ HCl, pH 8.8, 100 mM NaCl, pH: 8.8
Experiment: SAXS data collected at EMBL X33, DORIS III, DESY on 2011 May 27
RgGuinier 3.1 nm
Dmax 11.0 nm
VolumePorod 149 nm3