The C-Terminal Random Coil Region Tunes the Ca2+-Binding Affinity of S100A4 through Conformational Activation
Duelli A,
Kiss B,
Lundholm I,
Bodor A,
Petoukhov M,
Svergun D,
Nyitray L,
Katona G,
Csernoch L
PLoS ONE
9(5):e97654
(2014 May 15)
|
|
|
Sample: |
Protein S100-A4 dimer, 23 kDa Homo sapiens protein
|
Buffer: |
20 mM HEPES, 20 mM NaCl, 0.1 mM TCEP, pH: 7.5 |
Experiment: |
SAXS
data collected at BM29, ESRF on 2013 Mar 2
|
|
RgGuinier |
2.1 |
nm |
Dmax |
7.0 |
nm |
VolumePorod |
48 |
nm3 |
|
|