Interactions of ataxin-3 with its molecular partners in the protein machinery that sorts protein aggregates to the aggresome.

Bonanomi M, Mazzucchelli S, D'Urzo A, Nardini M, Konarev PV, Invernizzi G, Svergun DI, Vanoni M, Regonesi ME, Tortora P
Int J Biochem Cell Biol 51:58-64 (2014 Jun)

PMID: 24685680 doi: 10.1016/j.biocel.2014.03.015

Submitted to SASBDB: 2021 May 19 Published in SASBDB: 2021 May 31

SASDLH5 – Aggregation state of Ataxin-3 protein Sample: Ataxin-3 monomer, 41 kDa Homo sapiens protein Buffer: phosphate buffered saline (PBS), pH: 7.4 Experiment: SAXS data collected at EMBL X33, DORIS III, DESY on 2009 Dec 3 RgGuinier 6.9 nm Dmax 25.0 nm VolumePorod 425 nm3

SASDLJ5 – Aggregation state of tubulin protein Sample: Tubulin alpha-1A chain monomer, 50 kDa Homo sapiens protein Buffer: phosphate buffered saline (PBS), pH: 7.4 Experiment: SAXS data collected at EMBL X33, DORIS III, DESY on 2009 Dec 3 RgGuinier 7.0 nm Dmax 25.0 nm VolumePorod 340 nm3

SASDLK5 – Aggregation state of ataxin-3-tubulin complex Sample: Ataxin-3 monomer, 41 kDa Homo sapiens protein Tubulin alpha-1A chain monomer, 50 kDa Homo sapiens protein Buffer: phosphate buffered saline (PBS), pH: 7.4 Experiment: SAXS data collected at EMBL X33, DORIS III, DESY on 2009 Dec 3 RgGuinier 8.4 nm Dmax 30.0 nm VolumePorod 900 nm3