Structural insights into highly similar spatial organization of zinc-finger associated domains with a very low sequence similarity.

Bonchuk AN, Boyko KM, Nikolaeva AY, Burtseva AD, Popov VO, Georgiev PG
Structure (2022 May 5)
PMID: 35580610
doi: 10.1016/j.str.2022.04.009 		Submitted to SASBDB: 2021 Aug 22
Published in SASBDB:

SASDMG3 – Tetrameric zinc-finger associated domain of Drosophila Pita protein

LD15650p (Pita, isoform A) experimental SAS data
OTHER model
Sample: LD15650p (Pita, isoform A) tetramer, 52 kDa Drosophila melanogaster protein
Buffer: 20 mM Tris, 100 mM NaCl, 5 mM DTT, pH: 7.4
Experiment: SAXS data collected at BM29, ESRF on 2018 Jul 8
RgGuinier 2.4 nm
Dmax 7.6 nm
VolumePorod 62 nm3

SASDMH3 – Zinc-finger associated domain of Drosophila Pita protein L45A

LD15650p (Pita, isoform A; L45A) experimental SAS data
OTHER model
Sample: LD15650p (Pita, isoform A; L45A) dimer, 26 kDa Drosophila melanogaster protein
Buffer: 20 mM Tris, 100 mM NaCl, 5 mM DTT, pH: 7.4
Experiment: SAXS data collected at BM29, ESRF on 2018 Dec 17
RgGuinier 2.3 nm
Dmax 9.5 nm
VolumePorod 35 nm3

SASDMJ3 – Zinc-finger-associated domain from Drosophila Motif 1 binding protein (M1BP)

LD30467p (Motif 1 binding protein) experimental SAS data
OTHER model
Sample: LD30467p (Motif 1 binding protein) dimer, 22 kDa Drosophila melanogaster protein
Buffer: 20 mM Bis-Tris-Propane, 100 mM NaCl, 5 mM DTT, pH: 8.5
Experiment: SAXS data collected at BM29, ESRF on 2018 Dec 17
RgGuinier 2.3 nm
Dmax 9.1 nm
VolumePorod 33 nm3