Biophysical characterisation of human LincRNA-p21 sense and antisense Alu inverted repeats.

D'Souza MH, Mrozowich T, Badmalia MD, Geeraert M, Frederickson A, Henrickson A, Demeler B, Wolfinger MT, Patel TR
Nucleic Acids Res 50(10):5881-5898 (2022 Jun 10)
PMID: 35639511
doi: 10.1093/nar/gkac414
Submitted to SASBDB: 2021 Dec 8
Published in SASBDB:

SASDNL2 – LincRNA-p21 Sense Alu Inverted Repeat

LincRNA-p21 AluSx1 Sense RNA experimental SAS data
DAMMIN model
Sample: LincRNA-p21 AluSx1 Sense RNA monomer, 100 kDa Homo sapiens RNA
Buffer: 50mM HEPES,150 mM NaCl, 15 mM MgCl2, 3% glycerol, pH: 7.4
Experiment: SAXS data collected at B21, Diamond Light Source on 2021 Jul 1
RgGuinier 6.1 nm
Dmax 18.5 nm
VolumePorod 225 nm3

SASDNM2 – LincRNA-p21 Antisense Alu Inverted Repeat

LincRNA-p21 AluSx1 Antisense RNA experimental SAS data
DAMMIN model
Sample: LincRNA-p21 AluSx1 Antisense RNA monomer, 90 kDa Homo sapiens RNA
Buffer: 50mM HEPES,150 mM NaCl, 15 mM MgCl2, 3% glycerol, pH: 7.4
Experiment: SAXS data collected at B21, Diamond Light Source on 2021 Jul 1
RgGuinier 5.9 nm
Dmax 18.1 nm
VolumePorod 375 nm3