The Dimer Interface of the Membrane Type 1 Matrix Metalloproteinase Hemopexin Domain

Tochowicz A, Goettig P, Evans R, Visse R, Shitomi Y, Palmisano R, Ito N, Richter K, Maskos K, Franke D, Svergun D, Nagase H, Bode W, Itoh Y
Journal of Biological Chemistry 286(9):7587-7600 (2011 Mar)

doi: 10.1074/jbc.M110.178434
Submitted to SASBDB: 2021 Dec 21
Published in SASBDB:

SASDNU2 – Homodimerization of a membrane type 1 matrix metalloproteinase (MT1-MMP)

HemopexinHemopexin experimental SAS data
CUSTOM IN-HOUSE model
Sample: Hemopexin monomer, 23 kDa Homo sapiens protein
Hemopexin dimer, 46 kDa Homo sapiens protein
Buffer: 50 mM HEPES, 150 mM NaCl, 10 mM CaCl2, pH: 7.5
Experiment: SAXS data collected at EMBL X33, DORIS III, DESY on 2006 Nov 25
RgGuinier 2.3 nm
Dmax 8.0 nm
VolumePorod 48 nm3