Crystal Structures of Free and Ligand-Bound Forms of the TetR/AcrR-Like Regulator SCO3201 from Streptomyces coelicolor Suggest a Novel Allosteric Mechanism.

Werten S, Waack P, Palm GJ, Virolle MJ, Hinrichs W
FEBS J (2022 Aug 26)
PMID: 36017630
doi: 10.1111/febs.16606 		Submitted to SASBDB: 2022 Jan 23
Published in SASBDB:

SASDN75 – TetR/AcrR-like repressor SCO3201 from Streptomyces coelicor

Putative tetR-family transcriptional regulator experimental SAS data
PDB (PROTEIN DATA BANK) model
Sample: Putative tetR-family transcriptional regulator dimer, 47 kDa Streptomyces coelicolor (strain … protein
Buffer: 20 mM Tris/HCl, 400 mM NaCl, 50 mM imidazole, 1 mM DTT, pH: 8.5
Experiment: SAXS data collected at BM29, ESRF on 2014 May 2
RgGuinier 2.6 nm
Dmax 6.5 nm
VolumePorod 77 nm3