ARL15, a GTPase implicated in rheumatoid arthritis, potentially repositions its truncated N-terminus as a function of guanine nucleotide binding

Saini M, Upadhyay N, Dhiman K, Manjhi S, Kattuparambil A, Ghoshal A, Arya R, Dey S, Sharma A, Aduri R, Thelma B, Ashish F, Kundu S
International Journal of Biological Macromolecules 254:127898 (2024 Jan)

doi: 10.1016/j.ijbiomac.2023.127898

Submitted to SASBDB: 2022 Apr 9 Published in SASBDB: 2022 Dec 21

SASDNG9 – GIFT based desmeared and regularized SAXS profile on ADP-ribosylation factor-like protein 15 (apo conditions) Sample: ADP-ribosylation factor-like protein 15 monomer, 22 kDa Homo sapiens protein Buffer: 20 mM Tris, 100 mM NaCl, 1 mM PMSF, 10% glycerol, 1 mM DTT, pH: 8 Experiment: SAXS data collected at Anton Paar SAXSpace, CSIR - Institute of Microbial Technology (IMTech) on 2018 Jul 10 RgGuinier 1.8 nm Dmax 6.1 nm VolumePorod 33 nm3

SASDNH9 – GIFT based desmeared and regularized SAXS profile on ADP-ribosylation factor-like protein 15 with GDP Sample: ADP-ribosylation factor-like protein 15 monomer, 22 kDa Homo sapiens protein Buffer: 20 mM Tris, 100 mM NaCl, 1 mM PMSF, 10% glycerol, 1 mM DTT, pH: 8 Experiment: SAXS data collected at Anton Paar SAXSpace, CSIR - Institute of Microbial Technology (IMTech) on 2018 Jul 10 RgGuinier 2.0 nm Dmax 7.6 nm VolumePorod 38 nm3

SASDNJ9 – GIFT based desmeared and regularized SAXS profile on ADP-ribosylation factor-like protein 15 with GTP Sample: ADP-ribosylation factor-like protein 15 monomer, 22 kDa Homo sapiens protein Buffer: 20 mM Tris, 100 mM NaCl, 1 mM PMSF, 10% glycerol, 1 mM DTT, pH: 8 Experiment: SAXS data collected at Anton Paar SAXSpace, CSIR - Institute of Microbial Technology (IMTech) on 2018 Jul 10 RgGuinier 2.0 nm Dmax 7.7 nm VolumePorod 38 nm3