Biophysical characterisation of the structure of a SARS-CoV-2 self-amplifying—RNA (saRNA) vaccine
Myatt D,
Wharram L,
Graham C,
Liddell J,
Branton H,
Pizzey C,
Cowieson N,
Rambo R,
Shattock R
Biology Methods and Protocols
(2023 Feb 14)
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Sample: |
IMP-1 saRNA monomer, 3720 kDa RNA
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Buffer: |
5 mM Sodium Citrate, pH: 6.4 |
Experiment: |
SAXS
data collected at B21, Diamond Light Source on 2021 Apr 27
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RgGuinier |
23.8 |
nm |
Dmax |
85.9 |
nm |
VolumePorod |
6265 |
nm3 |
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