SAXS data based glycosylated models of human alpha-1-acid glycorprotein, a key player in health, disease and drug circulation.

Kalidas N, Peddada N, Pandey K, Ashish
J Biomol Struct Dyn :1-15 (2025 Mar 8)
PMID: 40056387
doi: 10.1080/07391102.2025.2475244 		Submitted to SASBDB: 2022 Jun 3
Published in SASBDB:

SASDPG4 – Alpha-1-acid glycoprotein at 283 K

Alpha-1-acid glycoprotein 1 experimental SAS data
PYMOL model
Sample: Alpha-1-acid glycoprotein 1 monomer, 22 kDa Homo sapiens protein
Buffer: phosphate buffered saline, pH: 7.4
Experiment: SAXS data collected at Anton Paar SAXSpace, CSIR - Institute of Microbial Technology (IMTech) on 2021 Jan 12
RgGuinier 2.6 nm
Dmax 7.5 nm
VolumePorod 83 nm3

SASDPH4 – Alpha-1-glycoprotein at 343 K

Alpha-1-acid glycoprotein 1 experimental SAS data
PYMOL model
Sample: Alpha-1-acid glycoprotein 1 monomer, 22 kDa Homo sapiens protein
Buffer: phosphate buffered saline, pH: 7.4
Experiment: SAXS data collected at Anton Paar SAXSpace, CSIR - Institute of Microbial Technology (IMTech) on 2021 Jan 12
RgGuinier 2.5 nm
Dmax 7.5 nm
VolumePorod 96 nm3