Clinically Linked Mutations in the Central Domains of Cardiac Myosin-Binding Protein C with Distinct Phenotypes Show Differential Structural Effects.
Nadvi NA,
Michie KA,
Kwan AH,
Guss JM,
Trewhella J
Structure
24(1):105-115
(2016 Jan 5)
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Sample: |
Cardiac myosin binding protein-C: domains C5-C6-C7 monomer, 36 kDa Homo sapiens protein
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Buffer: |
25 mM Tris-HCl, 250 mM NaCl, 2 mM TCEP, 0.02% sodium azide, pH: 7.5 |
Experiment: |
SAXS
data collected at SAXS/WAXS, Australian Synchrotron on 2015 Apr 18
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RgGuinier |
3.8 |
nm |
Dmax |
14.1 |
nm |
VolumePorod |
55 |
nm3 |
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