The intestinal MUC2 mucin C-terminus is stabilized by an extra disulfide bond in comparison to von Willebrand factor and other gel-forming mucins

Gallego P, Garcia-Bonete M, Trillo-Muyo S, Recktenwald C, Johansson M, Hansson G
Nature Communications 14(1) (2023 Apr 08)

doi: 10.1038/s41467-023-37666-8
Submitted to SASBDB: 2022 Jun 25
Published in SASBDB:

SASDPL4 – Human MUC2 mucin C-terminal dimer

Human Mucin 2 C-terminal experimental SAS data
DAMMIN model
Sample: Human Mucin 2 C-terminal dimer, 240 kDa Homo sapiens protein
Buffer: 25 mM HEPES, 100 mM NaCl, 10 mM CaCl2, pH: 7.4
Experiment: SAXS data collected at BM29, ESRF on 2020 Nov 20
RgGuinier 8.4 nm
Dmax 32.0 nm
VolumePorod 684 nm3