Structure of a 28.5 kDa duplex-embedded G-quadruplex system resolved to 7.4 Å resolution with cryo-EM.
Monsen RC,
Chua EYD,
Hopkins JB,
Chaires JB,
Trent JO
Nucleic Acids Res
(2023 Jan 30)
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Sample: |
Duplex-G4-duplex monomer, 29 kDa synthetic construct DNA
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Buffer: |
6 mM Na2HPO4, 2 mM NaH2PO4, 1 mM Na2EDTA, 185 mM KCl, pH: 7.2 |
Experiment: |
SAXS
data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2021 Jun 16
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RgGuinier |
3.2 |
nm |
Dmax |
13.3 |
nm |
VolumePorod |
59 |
nm3 |
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