Structural analysis of the housecleaning nucleoside triphosphate pyrophosphohydrolase MazG from Mycobacterium tuberculosis

Wang S, Gao B, Chen A, Zhang Z, Wang S, Lv L, Zhao G, Li J
Frontiers in Microbiology 14 (2023 Mar 1)

doi: 10.3389/fmicb.2023.1137279
Submitted to SASBDB: 2022 Nov 2
Published in SASBDB:

SASDQE5 – Nucleoside triphosphate pyrophosphohydrolase (1–185)

Nucleoside triphosphate pyrophosphohydrolase experimental SAS data
DAMMIF model
Sample: Nucleoside triphosphate pyrophosphohydrolase dimer, 41 kDa Mycobacterium tuberculosis (strain … protein
Buffer: 20 mM Tris-HCl, 100 mM NaCl, pH: 7.5
Experiment: SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2020 Dec 11
RgGuinier 2.7 nm
Dmax 8.4 nm
VolumePorod 64 nm3

SASDQ38 – Nucleoside triphosphate pyrophosphohydrolase (full-length)

Nucleoside triphosphate pyrophosphohydrolase experimental SAS data
DAMMIF model
Sample: Nucleoside triphosphate pyrophosphohydrolase dimer, 71 kDa Mycobacterium tuberculosis (strain … protein
Buffer: 20 mM Tris-HCl, 150 mM NaCl, pH: 8
Experiment: SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2022 Sep 4
RgGuinier 3.4 nm
Dmax 12.2 nm
VolumePorod 121 nm3