Atomistic structure of the SARS-CoV-2 pseudoknot in solution from SAXS-driven molecular dynamics.

He W, San Emeterio J, Woodside MT, Kirmizialtin S, Pollack L
Nucleic Acids Res (2023 Oct 11)
PMID: 37819014
doi: 10.1093/nar/gkad809 		Submitted to SASBDB: 2023 Feb 28
Published in SASBDB:

SASDRT6 – Wild type frameshifting pseudoknot from SARS CoV2 virus

Frameshifting pseudoknot from SARS CoV2, wild type experimental SAS data
Frameshifting pseudoknot from SARS CoV2, wild type Kratky plot
Sample: Frameshifting pseudoknot from SARS CoV2, wild type monomer, 23 kDa RNA
Buffer: 50 mM MOPS, 130 mM KCl, pH: 7.5
Experiment: SAXS data collected at 16-ID (LiX), National Synchrotron Light Source II (NSLS-II) on 2020 May 15
RgGuinier 2.7 nm
Dmax 10.5 nm
VolumePorod 40 nm3

SASDRU6 – Non frameshifting variant of SARS CoV2 frameshifting pseudoknot

Variant: non frameshifting pseudoknot from SARS CoV2 genome experimental SAS data
Variant: non frameshifting pseudoknot from SARS CoV2 genome Kratky plot
Sample: Variant: non frameshifting pseudoknot from SARS CoV2 genome monomer, 23 kDa RNA
Buffer: 50 mM MOPS, 130 mM KCl, pH: 7.5
Experiment: SAXS data collected at 16-ID (LiX), National Synchrotron Light Source II (NSLS-II) on 2020 Jun 12
RgGuinier 2.8 nm
Dmax 13.5 nm
VolumePorod 38 nm3