Tropomyosin 1-I/C coordinates kinesin-1 and dynein motors during oskar mRNA transport.

Heber S, McClintock MA, Simon B, Mehtab E, Lapouge K, Hennig J, Bullock SL, Ephrussi A
Nat Struct Mol Biol (2024 Jan 31)
PMID: 38297086
doi: 10.1038/s41594-024-01212-x 		Submitted to SASBDB: 2023 Mar 30
Published in SASBDB:

SASDRD8 – Drosophila melanogaster kinesin heavy chain

Kinesin heavy chain (A515T) experimental SAS data
Kinesin heavy chain (A515T) Kratky plot
Sample: Kinesin heavy chain (A515T) dimer, 221 kDa Drosophila melanogaster protein
Buffer: 25 mM HEPES/KOH, 150 mM NaCl, 1 mM MgCl2, 2 mM DTT, pH: 7.3
Experiment: SAXS data collected at BM29, ESRF on 2022 Feb 19
RgGuinier 10.0 nm
Dmax 45.0 nm
VolumePorod 920 nm3

SASDRE8 – Drosophila melanogaster kinesin heavy chain + Tropomyosin1-I/C

Kinesin heavy chain (A515T)GH09289p experimental SAS data
Kinesin heavy chain (A515T) GH09289p Kratky plot
Sample: Kinesin heavy chain (A515T) dimer, 221 kDa Drosophila melanogaster protein
GH09289p dimer, 96 kDa Drosophila melanogaster protein
Buffer: 25 mM HEPES/KOH, 150 mM NaCl, 1 mM MgCl2, 2 mM DTT, pH: 7.3
Experiment: SAXS data collected at BM29, ESRF on 2022 Feb 19
RgGuinier 8.7 nm
Dmax 45.0 nm
VolumePorod 840 nm3