The sequence–structure–function relationship of intrinsic ERα disorder
Du Z,
Wang H,
Luo S,
Yun Z,
Wu C,
Yang W,
Buck M,
Zheng W,
Hansen A,
Kao H,
Yang S
Nature
(2025 Jan 08)
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Sample: |
Estrogen receptor monomer, 20 kDa Homo sapiens protein
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Buffer: |
20 mM sodium phosphate, 150 mM NaCl, 0.5 mM EDTA, 0.1 mM PMSF, pH: 7.4 |
Experiment: |
SAXS
data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2019 Jul 21
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RgGuinier |
3.2 |
nm |
Dmax |
14.0 |
nm |
VolumePorod |
47 |
nm3 |
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Sample: |
Estrogen receptor monomer, 20 kDa Homo sapiens protein
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Buffer: |
20 mM sodium phosphate, 50 mM NaCl, 0.05 mM TCEP, pH: 7.4 |
Experiment: |
SAXS
data collected at 16-ID (LiX), National Synchrotron Light Source II (NSLS-II) on 2024 Jul 17
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RgGuinier |
3.6 |
nm |
Dmax |
16.0 |
nm |
VolumePorod |
70 |
nm3 |
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Sample: |
Estrogen receptor (mutant S118A) monomer, 20 kDa Homo sapiens protein
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Buffer: |
20 mM sodium phosphate, 150 mM NaCl, 0.5 mM EDTA, 0.1 mM PMSF, pH: 7.4 |
Experiment: |
SAXS
data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2019 Jul 21
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RgGuinier |
3.2 |
nm |
Dmax |
15.0 |
nm |
VolumePorod |
71 |
nm3 |
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Sample: |
Estrogen receptor (mutant S118D) monomer, 20 kDa Homo sapiens protein
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Buffer: |
20 mM sodium phosphate, 150 mM NaCl, 0.5 mM EDTA, 0.1 mM PMSF, pH: 7.4 |
Experiment: |
SAXS
data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2019 Jul 21
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RgGuinier |
3.5 |
nm |
Dmax |
16.0 |
nm |
VolumePorod |
62 |
nm3 |
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