Calcium modulates the tethering of BCOR-PRC1.1 enzymatic core to KDM2B via liquid-liquid phase separation.

Chen R, Shen F, Zhang Y, Sun M, Dong Y, Yin Y, Su C, Peng C, Liu J, Xu J
Commun Biol 7(1):1112 (2024 Sep 10)
PMID: 39256555
doi: 10.1038/s42003-024-06820-3 		Submitted to SASBDB: 2023 Jul 11
Published in SASBDB:

SASDS67 – Complex of BCL-6 corepressor linker-PUFD bound to Polycomb group RING finger protein 1 RAWUL, Lysine-specific demethylase 2B F-box-LRRs, and S-phase kinase-associated protein 1

BCL-6 corepressorLysine-specific demethylase 2BPolycomb group RING finger protein 1S-phase kinase-associated protein 1 experimental SAS data
OTHER model
Sample: BCL-6 corepressor monomer, 16 kDa Homo sapiens protein
Lysine-specific demethylase 2B monomer, 32 kDa Homo sapiens protein
Polycomb group RING finger protein 1 monomer, 13 kDa Homo sapiens protein
S-phase kinase-associated protein 1 monomer, 19 kDa Homo sapiens protein
Buffer: 20 mM Tris-HCl, 150 mM NaCl, pH: 7.5
Experiment: SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2022 Sep 1
RgGuinier 3.3 nm
Dmax 11.5 nm
VolumePorod 118 nm3

SASDS77 – Complex of BCL-6 corepressor ANK-linker-PUFD bound to Polycomb group RING finger protein 1 RAWUL, Lysine-specific demethylase 2B F-box-LRRs, and S-phase kinase-associated protein 1

Lysine-specific demethylase 2BPolycomb group RING finger protein 1S-phase kinase-associated protein 1BCL-6 corepressor experimental SAS data
OTHER model
Sample: Lysine-specific demethylase 2B monomer, 32 kDa Homo sapiens protein
Polycomb group RING finger protein 1 monomer, 13 kDa Homo sapiens protein
S-phase kinase-associated protein 1 monomer, 19 kDa Homo sapiens protein
BCL-6 corepressor monomer, 32 kDa Homo sapiens protein
Buffer: 20 mM Tris-HCl, 150 mM NaCl, pH: 7.5
Experiment: SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2021 Jul 16
RgGuinier 3.9 nm
Dmax 16.5 nm
VolumePorod 190 nm3