One substrate many enzymes virtual screening uncovers missing genes of carnitine biosynthesis in human and mouse.
Malatesta M,
Fornasier E,
Di Salvo ML,
Tramonti A,
Zangelmi E,
Peracchi A,
Secchi A,
Polverini E,
Giachin G,
Battistutta R,
Contestabile R,
Percudani R
Nat Commun
15(1):3199
(2024 Apr 13)
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Sample: |
L-threonine aldolase tetramer, 165 kDa Mus musculus protein
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Buffer: |
20 mM Tris, 150 mM NaCl, 1 mM EDTA, 1 mM DTT, pH: 7.8 |
Experiment: |
SAXS
data collected at BM29, ESRF on 2023 Feb 14
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RgGuinier |
3.7 |
nm |
Dmax |
10.6 |
nm |
VolumePorod |
209 |
nm3 |
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