Rapid simulation of glycoprotein structures by grafting and steric exclusion of glycan conformer libraries.

Tsai YX, Chang NE, Reuter K, Chang HT, Yang TJ, von Bülow S, Sehrawat V, Zerrouki N, Tuffery M, Gecht M, Grothaus IL, Colombi Ciacchi L, Wang YS, Hsu MF, Khoo KH, Hummer G, Hsu SD, Hanus C, Sikora M
Cell 187(5):1296-1311.e26 (2024 Feb 29)
PMID: 38428397
doi: 10.1016/j.cell.2024.01.034 		Submitted to SASBDB: 2023 Nov 28
Published in SASBDB:

SASDT35 – N-cadherin extracellular domains EC1-EC5

Cadherin-2 experimental SAS data
Cadherin-2 Kratky plot
Sample: Cadherin-2 dimer, 123 kDa Mus musculus protein
Buffer: 10 mM HEPES, 150 mM NaCl, 3 mM CaCl2, 0.02% NaN3, pH: 8
Experiment: SAXS data collected at 13A, Taiwan Photon Source, NSRRC on 2023 May 1
RgGuinier 8.8 nm
Dmax 40.0 nm
VolumePorod 496 nm3

SASDT45 – N-cadherin extracellular domains EC4-EC5

Cadherin-2 experimental SAS data
Cadherin-2 Kratky plot
Sample: Cadherin-2 monomer, 24 kDa Mus musculus protein
Buffer: 10 mM HEPES, 150 mM NaCl, 3 mM CaCl2, 0.02% NaN3, pH: 8
Experiment: SAXS data collected at 13A, Taiwan Photon Source, NSRRC on 2023 May 1
RgGuinier 3.4 nm
Dmax 12.6 nm
VolumePorod 63 nm3