Trypanosoma brucei Invariant Surface Glycoprotein 75 Is an Immunoglobulin Fc Receptor Inhibiting Complement Activation and Antibody-Mediated Cellular Phagocytosis.

Mikkelsen JH, Stødkilde K, Jensen MP, Hansen AG, Wu Q, Lorentzen J, Graversen JH, Andersen GR, Fenton RA, Etzerodt A, Thiel S, Andersen CBF
J Immunol (2024 Feb 23)
PMID: 38391367
doi: 10.4049/jimmunol.2300862
Submitted to SASBDB: 2023 Nov 29
Published in SASBDB:

SASDTP5 – Invariant surface glycoprotein 75 (N134A) amino acids 29-468

Invariant surface glycoprotein (N134A) experimental SAS data
CORAL model
Sample: Invariant surface glycoprotein (N134A) monomer, 49 kDa Trypanosoma brucei protein
Buffer: 20 mM Tris-HCl, 75 mM KCl, pH: 7.6
Experiment: SAXS data collected at EMBL P12, PETRA III on 2015 Aug 18
RgGuinier 3.6 nm
Dmax 15.0 nm
VolumePorod 127 nm3