Quaternary structure of the human Cdt1-Geminin complex regulates DNA replication licensing.
De Marco V,
Gillespie PJ,
Li A,
Karantzelis N,
Christodoulou E,
Klompmaker R,
van Gerwen S,
Fish A,
Petoukhov MV,
Iliou MS,
Lygerou Z,
Medema RH,
Blow JJ,
Svergun DI,
Taraviras S,
Perrakis A
Proc Natl Acad Sci U S A
106(47):19807-12
(2009 Nov 24)
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| Sample: |
Geminin dimer, 47 kDa Homo sapiens protein
DNA replication factor Cdt1 monomer, 60 kDa Homo sapiens protein
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| Buffer: |
25 mM Tris75 200 mM NaCl, pH: 7.5 |
| Experiment: |
SAXS
data collected at EMBL X33, DORIS III, DESY on 2006 Aug 13
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|
| RgGuinier |
2.9 |
nm |
| Dmax |
10.0 |
nm |
| VolumePorod |
70 |
nm3 |
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|
|
|
|
|
|
| Sample: |
Geminin dimer, 47 kDa Homo sapiens protein
DNA replication factor Cdt1 monomer, 60 kDa Homo sapiens protein
|
| Buffer: |
25 mM Tris75 200 mM NaCl, pH: 7.5 |
| Experiment: |
SAXS
data collected at EMBL X33, DORIS III, DESY on 2006 Oct 5
|
|
| RgGuinier |
3.8 |
nm |
| Dmax |
14.0 |
nm |
| VolumePorod |
120 |
nm3 |
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