Autoinhibition of ubiquitin-specific protease 8: insights into domain interactions and mechanisms of regulation

Caba C, Black M, Liu Y, DaDalt A, Mallare J, Fan L, Harding R, Wang Y, Vacratsis P, Huang R, Zhuang Z, Tong Y
Journal of Biological Chemistry :107727 (2024 Aug)

doi: 10.1016/j.jbc.2024.107727 		Submitted to SASBDB: 2024 May 24
Published in SASBDB:

SASDU39 – Nearly full-length monomeric Human Ubiquitin carboxyl-terminal hydrolase 8 (USP8) (7-1110)

Ubiquitin carboxyl-terminal hydrolase 8 experimental SAS data
DAMMIF model
Sample: Ubiquitin carboxyl-terminal hydrolase 8 monomer, 127 kDa Homo sapiens protein
Buffer: 25 mM Tris, 150 mM NaCl, pH: 7.5
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2022 Jun 18
RgGuinier 8.4 nm
Dmax 31.8 nm
VolumePorod 327 nm3