Structural insights into the enzymatic breakdown of azomycin-derived antibiotics by 2-nitroimdazole hydrolase (NnhA).

Ahmed FH, Liu JW, Royan S, Warden AC, Esquirol L, Pandey G, Newman J, Scott C, Peat TS
Commun Biol 7(1):1676 (2024 Dec 19)
PMID: 39702827
doi: 10.1038/s42003-024-07336-6 		Submitted to SASBDB: 2024 Aug 26
Published in SASBDB:

SASDVG6 – 2-nitroimidazole nitrohydrolase

2-nitroimidazole nitrohydrolase (T2I, G14D, K73R) experimental SAS data
REFMAC model
Sample: 2-nitroimidazole nitrohydrolase (T2I, G14D, K73R) hexamer, 258 kDa Mycobacterium sp. (strain … protein
Buffer: 25 mM Tris-HCl, 150 mM NaCl, 5% (v/v) glycerol, pH: 7.6
Experiment: SAXS data collected at BioSAXS, Australian Synchrotron on 2024 Aug 6
RgGuinier 4.6 nm
Dmax 12.6 nm
VolumePorod 363 nm3