Selective cargo and membrane recognition by SNX17 regulates its interaction with Retriever

Martín-González A, Méndez-Guzmán I, Zabala-Zearreta M, Quintanilla A, García-López A, Martínez-Lombardía E, Albesa-Jové D, Acosta J, Lucas M
EMBO Reports (2024 Dec 09)

doi: 10.1038/s44319-024-00340-1 		Submitted to SASBDB: 2024 Aug 27
Published in SASBDB:

SASDVQ6 – Retriever complex

VPS35 endosomal protein-sorting factor-likeVacuolar protein sorting-associated protein 29Vacuolar protein sorting-associated protein 26C experimental SAS data
ALPHAFOLD model
Sample: VPS35 endosomal protein-sorting factor-like monomer, 110 kDa Homo sapiens protein
Vacuolar protein sorting-associated protein 29 monomer, 21 kDa Homo sapiens protein
Vacuolar protein sorting-associated protein 26C monomer, 33 kDa Homo sapiens protein
Buffer: 50 mM Tris, 200 mM NaCl, 1 mM TCEP, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2022 Apr 28
RgGuinier 5.2 nm
Dmax 21.5 nm
VolumePorod 256 nm3

SASDVR6 – Vacuolar protein sorting-associated protein 26C (VPS26C)

Vacuolar protein sorting-associated protein 26C experimental SAS data
ALPHAFOLD model
Sample: Vacuolar protein sorting-associated protein 26C monomer, 33 kDa Homo sapiens protein
Buffer: 50 mM Tris, 150 mM NaCl, 1 mM TCEP,, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2021 Apr 22
RgGuinier 2.7 nm
Dmax 9.4 nm
VolumePorod 44 nm3