Unraveling the molecular grammar and the structural transitions underlying the fibrillation of a viral fibrillogenic domain.

Gondelaud F, Leval J, Arora L, Walimbe A, Bignon C, Ptchelkine D, Brocca S, Mukhopadyay S, Longhi S
Protein Sci 34(3):e70068 (2025 Mar)
PMID: 39985377
doi: 10.1002/pro.70068 		Submitted to SASBDB: 2024 Oct 14
Published in SASBDB:

SASDVC8 – Hendra virus protein P/V/W PNT3 domain

Protein W experimental SAS data
Hendra virus protein P/V/W PNT3 domain Rg histogram
Sample: Protein W monomer, 15 kDa Hendra virus (isolate … protein
Buffer: 20 mM HEPES, 150 mM NaCl, pH: 7.2
Experiment: SAXS data collected at BM29, ESRF on 2023 Jun 13
RgGuinier 3.4 nm
Dmax 13.5 nm
VolumePorod 42 nm3

SASDVD8 – Hendra virus protein P/V/W PNT3 low-K domain

Protein W (artificial PNT3 variant - low-kappa) experimental SAS data
Hendra virus protein P/V/W PNT3 low-K domain Rg histogram
Sample: Protein W (artificial PNT3 variant - low-kappa) monomer, 15 kDa Hendra virus (isolate … protein
Buffer: 20 mM HEPES, 150 mM NaCl, pH: 7.2
Experiment: SAXS data collected at BM29, ESRF on 2023 Jun 13
RgGuinier 3.8 nm
Dmax 18.0 nm
VolumePorod 48 nm3

SASDVE8 – Hendra virus protein P/V/W PNT3 high-K domain

Protein W (artificial PNT3 variant - high-kappa) experimental SAS data
Hendra virus protein P/V/W PNT3 high-K domain Rg histogram
Sample: Protein W (artificial PNT3 variant - high-kappa) monomer, 15 kDa Hendra virus (isolate … protein
Buffer: 20 mM HEPES, 150 mM NaCl, pH: 7.2
Experiment: SAXS data collected at SWING, SOLEIL on 2024 Apr 5
RgGuinier 3.1 nm
Dmax 14.7 nm
VolumePorod 54 nm3