Insight into the structure and interactions of the M. tuberculosis Mce-associated membrane proteins Mam1A-1D

Hynönen M, Perumal P, Hynönen N, Doutch J, Ma K, Venkatesan R
(2025 Mar 26)

doi: 10.1101/2025.03.26.645568 		Submitted to SASBDB: 2025 Mar 26
Published in SASBDB:

SASDXF2 – Probable conserved Mce associated membrane protein (Mam1Adelta106) from M.tuberculosis

Probable conserved Mce associated membrane protein experimental SAS data
ALPHAFOLD model
Sample: Probable conserved Mce associated membrane protein tetramer, 59 kDa Mycobacterium tuberculosis (strain … protein
Buffer: 50mM Tris, 500mM NaCl, pH: 8.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2019 Dec 10
RgGuinier 3.2 nm
Dmax 90.0 nm
VolumePorod 90 nm3

SASDXG2 – Probable conserved Mce associated membrane protein (Mam1Adelta106) from M.tuberculosis (SANS)

Probable conserved Mce associated membrane protein experimental SAS data
DAMFILT model
Sample: Probable conserved Mce associated membrane protein tetramer, 59 kDa Mycobacterium tuberculosis (strain … protein
Buffer: 50 mM Tris, 500 mM NaCl, D-C12E9, pH: 8.5
Experiment: SANS data collected at SANS2D, ISIS Neutron and Muon Source on 2019 Dec 10
RgGuinier 2.6 nm
Dmax 8.5 nm
VolumePorod 33 nm3