Functional and structural insight into properdin control of complement alternative pathway amplification.

Pedersen DV, Roumenina L, Jensen RK, Gadeberg TA, Marinozzi C, Picard C, Rybkine T, Thiel S, Sørensen UB, Stover C, Fremeaux-Bacchi V, Andersen GR
EMBO J 36(8):1084-1099 (2017 Apr 13)
PMID: 28264884
doi: 10.15252/embj.201696173 		Submitted to SASBDB: 2017 Jan 2
Published in SASBDB:

SASDB59 – Recombinant monomeric human Properdin

Human recombinant Properdin TSR 0-3Human recombinant Properdin TSR 4-6 experimental SAS data
CORAL model
Sample: Human recombinant Properdin TSR 0-3 monomer, 25 kDa Homo sapiens protein
Human recombinant Properdin TSR 4-6 monomer, 24 kDa Homo sapiens protein
Buffer: 10 mM HEPES 150 mM NaCl, pH: 7.2
Experiment: SAXS data collected at EMBL P12, PETRA III on 2015 Aug 16
RgGuinier 5.1 nm
Dmax 18.0 nm

SASDB69 – E244K monomeric human Properdin

E244K Human Properdin experimental SAS data
CORAL model
Sample: E244K Human Properdin monomer, 49 kDa Homo sapiens protein
Buffer: 10 mM HEPES 150 mM NaCl, pH: 7.2
Experiment: SAXS data collected at EMBL P12, PETRA III on 2016 Jul 27
RgGuinier 4.1 nm
Dmax 15.0 nm